18. Neapolitan Mastiff

The Neapolitan Mastiff is known for its loose, wrinkled skin and massive size. With roots in ancient Rome, these dogs have a prehistoric appearance. They are gentle giants, weighing up to 150 pounds and standing 24 to 31 inches tall. Their wrinkled faces and droopy skin once offered protection in battle. Despite their intimidating appearance, Neapolitan Mastiffs are loving and gentle with family. They are protective but rarely aggressive without reason. Their short coat comes in black, blue, mahogany, and tawny. Early socialization and positive training help manage their strong-willed nature.